发明名称 |
LUCIFERASE SEQUENCES UTILIZING INFRARED-EMITTING SUBSTRATES TO PRODUCE ENHANCED LUMINESCENCE |
摘要 |
Provided herein are isolated polynucleotide encoding modified click beetle luciferase polypeptides that have enhanced luminescence and longer wavelength near-infrared signals. The disclosure also relates to near-infrared bioluminescence systems that include said modified click beetle luciferase polypeptides and novel luciferin derivatives, as well as methods of using said modified click beetle luciferase polypeptides and bioluminescence systems. |
申请公布号 |
WO2016040788(A1) |
申请公布日期 |
2016.03.17 |
申请号 |
WO2015US49661 |
申请日期 |
2015.09.11 |
申请人 |
PROMEGA CORPORATION |
发明人 |
ENCELL, LANCE, P.;HALL, MARY, P.;WOOD, KEITH, V.;WOOD, MONIKA, G. |
分类号 |
C12Q1/66;C12N9/02;C12N15/53 |
主分类号 |
C12Q1/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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