Systems and methods for magnetized stent having growth-promoting properties

摘要

Embodiments relate to systems and methods for magnetized stent having growth-promoting properties. A stent assembly comprising a tubular elongated body having a magnetized region and a tissue nidus area is inserted beneath the orifice of a vascular aneurysm. The magnetic region can serve to attract and position both residual red blood cells and magnetically nano-ireated growth-promoting cells to the orifice area of the aneurysm. The outer circumference of the tubular elongated body can act as a floor or scaffold for regenerated smooth vascular muscle cells. In embodiments, the tissue nidus area can be provided on the exterior stent, while the magnetized region is provided on the interior stent, of a stent-in-stent structure. In embodiments, the exterior stent is made of biodegradable material which gradually dissolves or dissipates in situ.

主权项

1. A stent assembly, comprising:
a tubular elongated body having an inner and outer surface, wherein the tubular elongated body comprises: a tissue nidus area comprising growth-promoting material positionable underneath an orifice of a vascular aneurysm, wherein the tissue nidus area is provided on the outer surface of the tubular elongated body and comprises an area of the tubular elongated body coated with muscle cells comprising magnetic nanoparticles; and a magnetized region, alignable with the tissue nidus area, for applying a magnetic field to the orifice of the vascular aneurysm to promote tissue growth on the tissue nidus area and across the orifice.