VIRAL PROTEINS AS IMMUNOMODULATORY AGENTS AND VACCINE COMPONENTS

摘要

The invention provides compositions and methods involving viral envelope polypeptides and peptides for use in modulating immune responses, including inhibition inflammation related to pathogenic T-cell activation. In addition, modification of the viral sequences responsible for modulating immune response provides for improved vaccine formulations.

主权项

1. A method of inhibiting immune cell activation comprising administering to a mammalian subject in need thereof an RNA virus envelope peptide or polypeptide comprising an immunomodulatory domain.