| 发明名称 |
Methods of Reducing Kinase Inhibitor Resistance |
| 摘要 |
Methods, compounds and kits relating to treating cancer, reducing kinase inhibitor or resistance, and reducing or preventing diminished ectodomain shedding are described. |
| 申请公布号 |
US2016067250(A1) |
申请公布日期 |
2016.03.10 |
| 申请号 |
US201514690001 |
申请日期 |
2015.04.17 |
| 申请人 |
Massachusetts Institute of Technology |
发明人 |
Gertler Frank B.;Griffith Linda G.;Lauffenburger Douglas A.;Meyer Aaron Samuel;Miller Miles Aaron;Oudin Madeleine |
| 分类号 |
A61K31/519;A61K31/502;A61K39/395;A61K31/437;A61K31/506;A61K31/381 |
主分类号 |
A61K31/519 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a cancer in an individual comprising administering a therapeutically effective amount of a MAP kinase inhibitor and one or more of an AXL inhibitor, a Met inhibitor, and a PI3K inhibitor. |
| 地址 |
Cambridge MA US |
