发明名称 METHOD FOR OBTAINING PYRIMIDINE DERIVATIVES
摘要 FIELD: chemistry.SUBSTANCE: invention relates to crystalline form of monohydrochloride salt of formula Acompound in polymorphic form A, where said monohydrochloride salt has in diffraction of X-rays peak at diffraction angle 2θ 9.9±0.3° and 20.0±0.3°.EFFECT: said crystalline form has low moisture-absorption in comparison with free base and monohydrate monochloride, which makes it possible to provide composition stability with low risk of chemical destruction.4 cl, 10 tbl, 14 dwg, 16 ex
申请公布号 RU2576619(C2) 申请公布日期 2016.03.10
申请号 RU20130120326 申请日期 2011.09.29
申请人 NOVARTIS AG 发明人 KALENNI DZHON VINSENT;DE-LA-KRUS MERILIN;FLUBAKHER DITMAR;GUN BAOTSIN;KAPA PRASAD KOTESVARA;KARPINSKI POTR KH.;LJU KHOJ;MISHEL PASKAL;MOSE RASMUS;TESTA MARIA KATERINA;VAJKOLE LILADKHAR MARLIDKHAR
分类号 C07D413/14;A61K31/5377;A61P35/00;C07D413/04 主分类号 C07D413/14
代理机构 代理人
主权项
地址