| 发明名称 |
METHOD OF TREATING EYE DISEASES ACCOMPANIED BY OXIDATIVE STRESS |
| 摘要 |
FIELD: medicine.SUBSTANCE: invention is intended for treating eye diseases accompanied by oxidative stress. Superoxide dismutase is introduced into composition of calcium-phosphate biodegradable nanoparticles coated with disaccharide, with radius of up to 350 nm and in the range of enzymatic activity from 20 to 500 kunit/ml and is entered in eye's conjunctival cavity.EFFECT: method enables higher therapeutic effectiveness of superoxide dismutase due to increased capacity of this enzyme to reduce intensity of oxidative stress in ophthalmic diseases.1 cl, 6 ex |
| 申请公布号 |
RU2577236(C1) |
申请公布日期 |
2016.03.10 |
| 申请号 |
RU20140150495 |
申请日期 |
2014.12.15 |
| 申请人 |
FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "MOSKOVSKIJ NAUCHNO-ISSLEDOVATELSKIJ INSTITUT GLAZNYKH BOLEZNEJ IMENI GELMGOLTSA" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII;FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO OBRAZOVANIJA "MOSKOVSKIJ GOSUDARSTVENNYJ UNIVERSITET IMENI M.V. LOMONOSOVA" |
发明人 |
CHESNOKOVA NATALJA BORISOVNA;KOST OLGA ALEKSEEVNA;NIKOLSKAJA IRINA IVANOVNA;BEZNOS OLGA VALEREVNA;GALITSKIJ VLADIMIR ALEKSEEVICH;BEJSHENOVA GULMIRA ALIMOVNA;KLJACHKO NATALJA LVOVNA;KABANOV ALEKSANDR VIKTOROVICH |
| 分类号 |
A61F9/00;A61K33/08;A61P27/02 |
主分类号 |
A61F9/00 |
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