发明名称 COMPOUNDS, COMPOSITIONS AND METHODS SUITABLE FOR CHOLESTEROL MOBILISATION
摘要 FIELD: chemistry.SUBSTANCE: invention relates to organic chemistry, specifically to a novel heterocyclic compound of general formula(II) or to a pharmaceutically acceptable salt, where each Ris -H; each Ris independently -H, -OH, NH(methyl), -N(methyl)(methyl) or -O-methyl; each of Q, Qand Qis independently CRor N; X is CHRor O; and each m is 1. The invention also relates to a pharmaceutical composition based on a compound of formula (II), a treatment method based on the use of a compound of formula (II), and a method of determining the level of activity of P2Y13 in a subject, based on the use of a compound of formula (II).EFFECT: obtaining novel compounds having agonistic activity with respect to the P2Y13 receptor.18 cl, 28 dwg, 4 tbl, 20 ex
申请公布号 RU2576402(C2) 申请公布日期 2016.03.10
申请号 RU20130122834 申请日期 2011.10.18
申请人 SERENIS TERAPJUTIKS KHOLDING SA 发明人 ONISIJU DANIELA KARMEN;DASSE ZHAN-LUI ANRI;BARBARA RONALD;KOCHUBEJ VALERIJ;KOVALSKIJ DMITRIJ;RODIN OLEG GENNADEVICH;ZHOFFRUA OTTO;RZEPILA ANNA
分类号 C07D403/14;A61K31/4427;A61K31/506;A61K31/5377;A61P3/00;C07D401/14;C07D413/14 主分类号 C07D403/14
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