Method and apparatus for the preparation of a vascularized bioartificial tissue

摘要

In a process to cultivate cardiac tissue in a reactor, living cells are introduced into the reactor with nutrients and a matrix. The transparent vessel is externally supplied with nutrients and crossed by a series of ladder-like transverse tubes, resulting in a cell tissue culture with an artificial vascular structure. An Independent claim is also included for a reactor assembly in which the process takes place. The reactor assembly has parallel transparent sidewalls through which the culture progress may be observed. The reactor is made either from natural human or animal tissue, or from a biologically compatible polymer. The reactor sidewalls have a series of side perforations or are permeable. The vessel interior is seeded at intervals with tissue growth-promoting substances.