发明名称 |
PIPERAZINEDIONES AS OXYTOCIN RECEPTOR ANTAGONISTS |
摘要 |
Compounds of formula (I)
wherein R 1 is 2-indanyl, R 2 is 1-methylpropyl, R 3 is a group selected from 2, 6-dimethyl-3-pyridyl or 4,6-dimethyl-3-pyridyl, R 4 represents methyl and R 5 represents hydrogen or methyl or, R 4 and R 5 together with the nitrogen atom to which they are attached represent morpholino and pharmaceutically acceptable derivatives thereof are described, as are processes for their preparation, pharmaceutical compositions containing them and their use in medicine, particularly their use as oxytocin antagonists. |
申请公布号 |
HK1106499(A1) |
申请公布日期 |
2016.03.04 |
申请号 |
HK20070107960 |
申请日期 |
2007.07.23 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BORTHWICK, ALAN, DAVID;HICKEY, DEIRDRE, MARY, BERNADETTE;LIDDLE, JOHN;MASON, ANDREW, MCMURTRIE |
分类号 |
C07D;A61K;A61P;C07D401/06 |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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