发明名称 DIPHENYLMETHANE COMPOUND
摘要 The present invention aims to provide a compound superior in broad utility and stability, which is useful as a protecting reagent (anchor) of amino acid and/or peptide in liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide (—CONHR)-type, an organic synthesis reaction method (particularly peptide liquid phase synthesis method) using the compound, and a kit for peptide liquid phase synthesis containing the compound, and has found that the object can be achieved by a particular compound having a diphenylmethane skeleton.
申请公布号 US2016060198(A1) 申请公布日期 2016.03.03
申请号 US201514839111 申请日期 2015.08.28
申请人 AJINOMOTO CO., INC. 发明人 TAKAHASHI Daisuke
分类号 C07C43/23;C07K1/06 主分类号 C07C43/23
代理机构 代理人
主权项 1. A diphenylmethane compound represented by the formula (I): wherein Y is a hydroxyl group;k and l are each independently an integer of 0-5 and k+l is not 0;Ra in the number of k and Rb in the number of l are each independently an organic group having an aliphatic hydrocarbon group, wherein, in the organic group(s) in the number of (k+l), each having an aliphatic hydrocarbon group, the total carbon number of the aliphatic hydrocarbon groups is not less than 16;ring A optionally further has substituent(s) besides Ra; andring B optionally further has substituent(s) besides Rb.
地址 Tokyo JP