| 发明名称 |
RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS |
| 摘要 |
Provided herein is technology relating to imaging agents for positron emission tomography (PET) and particularly, but not exclusively, to a gonadotropin-releasing hormone (GnRH) antagonist radiolabeled with positron emitting nuclides and to methods of visualizing GnRH receptors in the central nervous system by PET from administration of such compounds to warm-blooded animals for diagnostic purposes. |
| 申请公布号 |
US2016058895(A1) |
申请公布日期 |
2016.03.03 |
| 申请号 |
US201414784998 |
申请日期 |
2014.04.18 |
| 申请人 |
OSLO UNIVERSITETSSYKEHUS HF |
发明人 |
Olberg Dag Erlend;Haraldsen Ira Hebold;Klaveness Jo |
| 分类号 |
A61K51/04;C07D307/68;C07D405/12 |
主分类号 |
A61K51/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound having the structure according to one of the following:or a salt, a free base, or a combination thereof, wherein X is O or C; Y is C or N; Z is C or N; and A is one of the following: |
| 地址 |
Olso NO |
