Methods for Cancer Treatment

摘要

Residual, refractory or relapsed cancer is treated by immunostimulation in the presence of allogeneic immune effector cells, optimally in combination with radiation therapy. The methods of the disclosure induce a systemic allogeneic anti-tumor immune response that results in tumor regression in untreated sites of disease, i.e. non-injected, non-irradiated, etc.

主权项

1. A method of treating a cancer in a subject, the method comprising administering to the subject an immunostimulant in combination with irradiation, wherein said irradiation induces a systemic allogeneic anti-tumor T-cell immune response that results in tumor regression in untreated sites of disease, and wherein the subject has undergone hematopoietic cell transplantation and is a chimera prior to said administering.