METHOD OF FABRICATING CELL ARRAYS AND USES THEREOF

摘要

The present disclosure provides a fabrication process that results in creating large arrays of living cells, such as stem cells, which are subsequently exposed to nanoliter quantities of compounds to test the efficacy on cellular metabolism.

主权项

1. A method of fabricating and dosing a stem cell array, comprising:
providing a mixture of cells and a UV curable hydrogel matrix; applying a volume of the mixture in N×N array to a support and optionally providing for a specific geometry for the applied volume; exposing the support to UV light to cure each volume in the array and optionally incubating the array under conditions that provide for cell viability; and contacting the array with one or more compounds.