发明名称 PHARMACEUTICAL COMPOSITIONS COMPRISING GOLD COMPOUND FOR PREVENTING OR TREATING FIBROSIS OR CIRRHOSIS OF THE LIVER
摘要 The present invention relates to a pharmaceutical composition for the prevention or treatment of liver fibrosis or liver cirrhosis. More specifically, the composition includes gold preparations. According to the present invention, the pharmaceutical or dietary supplement composition includes the gold preparations as an active ingredient in order to accelerate the transformation of macrophages and increase the expression of TREM-2, thereby suppressing the activation of stellate cells and preventing, alleviating, and treating liver fibrosis or liver cirrhosis. The gold preparations, and more specifically, the sodium aurothiomalate or aurothioglucose similar to auranofin and the auranofin are proven to have little side effects after being used to treat other purposes (rheumatoid arthritis) for an extended period of time.
申请公布号 KR20160023574(A) 申请公布日期 2016.03.03
申请号 KR20150116396 申请日期 2015.08.19
申请人 SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION 发明人 KANG, KEON WOOK;KIM, NA YOUN;YOON, KYUNG ROK
分类号 A61K31/7135;A61K33/24 主分类号 A61K31/7135
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