| 发明名称 |
SUBSTITUTED5-(3,5-DIMETHYLISOXAZOL-4-YL)INDOLINE-2-ONES |
| 摘要 |
Disclosed are substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compounds, pharmaceutical compositions comprising at least one such 4 substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compound processes for the preparation thereof, and the use thereof for inhibiting BET family of bromodomains and for treating disorders mediated thereby, such as certain cancers. |
| 申请公布号 |
EP2989096(A1) |
申请公布日期 |
2016.03.02 |
| 申请号 |
EP20140788064 |
申请日期 |
2014.04.14 |
| 申请人 |
BEIGENE, LTD. |
发明人 |
REN, BO;ZHOU, CHANGYOU;WANG, HEXIANG |
| 分类号 |
C07D413/04;A61K31/41;A61K31/422;A61K31/454;A61K31/496;A61K31/5377;A61K45/06;A61P35/00;C07D209/04;C07D413/14 |
主分类号 |
C07D413/04 |
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