摘要 |
The present invention provides a prophylactic or therapeutic agent, a pharmaceutical composition and a health-promoting food, which are used for human or other animal for the inhibition of the onset or progress of liver cancer, namely, an inhibitor of the onset or progress of liver cancer, which contains isoleucine, leucine and valine as active ingredients, wherein the weight ratio of isoleucine, leucine and valine is preferably 1:1.5 to 2.5:0.8 to 1.7 and the daily dose is 2.0 g to 50.0 g. |
代理机构 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A method for treating liver cancer in a subject in need thereof, which comprises administering an effective amount of a therapeutic composition to said subject in need thereof,
wherein said therapeutic composition consists of isoleucine, leucine, valine, one or more pharmacologically acceptable carrier, and, optionally, at least one additional drug for treating liver disease selected from the group consisting of an interferon, glycyrrhizin, ursodeoxycholic acid, Ribavirin, and Chinese medicine sho-saiko-to, wherein said isoleucine, leucine, and valine are administered in a weight ratio of 1:1.9 to 2.2:1.1 to 1.3, wherein said subject is a patient with liver cirrhosis, wherein said pharmacologically acceptable carrier is one or more excipient, binder, lubricant, solvent, disintegrant, dissolution aid, suspending agent, emulsifier, isotonicity agent, stabilizer, soothing agent, preservative, antioxidant, corrigent, coloring agent, or a mixture thereof, wherein said excipient is one or more excipient selected from the group consisting of a saccharide, a starch, a cellulose, calcium carbonate, and kaolin, wherein said stabilizer is selected from the group consisting of polyethylene glycol, and sodium dextran sulfate, and wherein said antioxidant is selected from the group consisting of subsulfate and ascorbic acid. |