发明名称 COMBINATION AND COMPOSITION OF A SELECTIVE AND SPECIFIC SINUS NODE ICURRENT INHIBITOR AND AN AGENT THAT INHIBITS ANGIOTENSIN-CONVERTING ENZYME, AND USE THEREOF FOR TREATING HEART FAILURE
摘要 Use of the combination and composition of a selective and specific sinus node Icurrent inhibitor ivabradine or N-{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxo-1-propanamine and an agent that inhibits angiotensin-converting enzyme and which is perindopril or one of its addition salts with a pharmaceutically acceptable base, or hydrates or crystalline forms thereof, in obtaining medicaments intended for the treatment of heart failure having preserved systolic function.
申请公布号 EA022612(B1) 申请公布日期 2016.02.29
申请号 EA20110000773 申请日期 2011.06.14
申请人 LES LABORATOIRES SERVIER 发明人 THUILLEZ CHRISTIAN;MULDER PAULUS;VILAINE JEAN-PAUL;FRATACCI MARIE-DOMINIQUE;LEREBOURS-PIGEONNIERE GUY;FELDMAN LUC;ROUSSEL JEROME
分类号 A61K31/55;A61K31/403;A61P9/04 主分类号 A61K31/55
代理机构 代理人
主权项
地址