发明名称 HIGH DOSAGE STRENGTH TABLETS OF RUCAPARIB
摘要 A tablet including high dosage of 8-fluoro-2-(4- [(methylamino)methyl]phenyl)-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one camsylate salt has been disclosed. The invention is directed to high dosage strength tablets of rucaparib. In some embodiments, the tablet includes 45-90% w/w njcaparib camsylate. In some embodiments, the dry granulated tablet includes 45-90% w/w rucaparib camsylate. One such embodiment is a tablet containing at least 200 mg rucaparib. Another embodiment is a tablet containing at least 300 mg rucaparib.
申请公布号 WO2016028689(A1) 申请公布日期 2016.02.25
申请号 WO2015US45522 申请日期 2015.08.17
申请人 CLOVIS ONCOLOGY, INC. 发明人 ETTER, JEFFREY
分类号 A61K31/55 主分类号 A61K31/55
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