TAURINE COMPOSITIONS SUITABLE FOR INHALATION

摘要

The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolisation.

主权项

1. A method for preparing conditioned taurine, the method comprising
a conditioning step, wherein the conditioning step is a spray drying step, to produce taurine that: (a) demonstrates no significant net change in the D90 (±20%) after 7 days of ambient storage and (b) have a particle size D90 of <20 μm, but more preferably <10 μm after 7 days of ambient storage;