发明名称 |
Preparation, Uses And Solid Forms Of Obeticholic Acid |
摘要 |
The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of obeticholic acid. |
申请公布号 |
AU2016200832(A1) |
申请公布日期 |
2016.02.25 |
申请号 |
AU20160200832 |
申请日期 |
2016.02.09 |
申请人 |
INTERCEPT PHARMACEUTICALS, INC. |
发明人 |
STEINER, ANDRE;WAENERLUND POULSEN, HEIDI;JOLIBOIS, EMILIE;REWOLINSKI, MELISSA;GROSS, RALF;SHARP, EMMA;DUBAS-FISHER, FIONA;EBERLIN, ALEX |
分类号 |
C07J9/00;A61K31/575;A61P1/16;C07J51/00 |
主分类号 |
C07J9/00 |
代理机构 |
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代理人 |
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地址 |
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