| 摘要 |
The present invention relates to a functional derivative of a Photoactive Yellow Protein (PYP), or a functional fragment thereof, for fluorescently labelling particles, e.g. proteins, or surfaces, which is capable of binding reversibly a fluorogenic chromophore of formula (I), and which is capable of enhancing the brightness of the said fluorogenic chromophore upon complexation thereto; and of inducing the spectral shift of the said fluorogenic chromophore through the ionization of an auxochromic group thereof. |
