发明名称 |
METHODS FOR THE DEVELOPMENT OF VACCINES BASED ON OLIGOSACCHARIDE-OLIGONUCLEOTIDE CONJUGATES |
摘要 |
Described herein are oligosaccharide-oligonucleotide conjugates useful as vaccines against one or more human or veterinary therapeutic indications, and methods of synthesizing and identifying them. The conjugates may be identified using non-human antibodies as binding targets, thereby expanding the power and scope of the invention. Efficacious conjugates may be identified through an iterative screening process. |
申请公布号 |
US2016051690(A1) |
申请公布日期 |
2016.02.25 |
申请号 |
US201514744985 |
申请日期 |
2015.06.19 |
申请人 |
Brandeis University |
发明人 |
KRAUSS Isaac J.;HEDSTROM Lizbeth K.;MACPHERSON Iain S. |
分类号 |
A61K47/48;C12N7/00;A61K39/21 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
1. (canceled) |
地址 |
Waltham MA US |