| 发明名称 |
METHODS OF TREATING FGF21-ASSOCIATED DISORDERS |
| 摘要 |
The invention relates to the identification of new polypeptide and protein variants of fibroblast growth factor 21 (FGF21) that have improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions. |
| 申请公布号 |
US2016051628(A1) |
申请公布日期 |
2016.02.25 |
| 申请号 |
US201514676863 |
申请日期 |
2015.04.02 |
| 申请人 |
BOETTCHER Brian R.;LOEW Andreas;CAPLAN Shari L.;DANIELS Douglas S.;GEIERSTANGER Bernhard H.;HAMAMATSU Norio;LICHT Stuart;WELDON Stephen Craig |
发明人 |
BOETTCHER Brian R.;LOEW Andreas;CAPLAN Shari L.;DANIELS Douglas S.;GEIERSTANGER Bernhard H.;HAMAMATSU Norio;LICHT Stuart;WELDON Stephen Craig |
| 分类号 |
A61K38/18;A61K47/48;C07K14/50 |
主分类号 |
A61K38/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A polypeptide variant having a sequence selected from SEQ ID NO:5-49. |
| 地址 |
Winchester MA US |
