摘要 |
The present invention relates to the rohitukine (5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-4H-chromen-4-ones) analogs of formula A and pharmaceutically acceptable salts thereof. In addition, the invention relates to pharmaceutically acceptable compositions comprising at least one such compound, and methods of using the compounds for treating or preventing various proliferative disorders such as melanoma, leukemia, breast cancer and prostate cancer etc. [insert Formula A here] wherein, n=0 or 1, when n=1, the dotted line indicates the double bond. |
申请人 |
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH |
发明人 |
VISHWAKARMA, RAM ASREY;BHARATE, SANDIP BIBISHAN;BHUSHAN, SHASHI;MONDHE, DILIP MANIKRAO;JAIN, SHREYANS KUMAR;MEENA, SAMDARSHI;GURU, SANTOSH KUMAR;PATHANIA, ANUP SINGH;KUMAR, SURESH;BEHL, AKANKSHA;MINTOO, MUBASHIR JAVED;BHARATE, SONALI SANDIP;JOSHI, PRASHANT |