摘要 |
Provided is a controlled-release preparation administered orally once a day that exhibits an optimum pharmacological clinical effect, prepared in the form of a bilayered tablet, a dual tablet, or a multilayered tablet including an immediate-release layer containing aceclofenac, a water-soluble additive, an insoluble additive, a solubilizer, a disintegrating agent and a filler, and a slow-release layer containing aceclofenac, a slow-release base, a disintegrating agent, a binder, a filler, a fluidizer, a solubilizer, and a lubricant. |
申请人 |
Korea United Pharm, Inc. |
发明人 |
LEE, Beom Jin;JUNG, Won-Tae;CHOI, Youn Woong;NAM, Kyu Yeol;CHO, Sang-Min;JANG, Jae Sang;CHOI, Min-Ji |