发明名称 M cells and artificial skin sheet
摘要 [Problem] To provide M cells having excellent strength and anti-allergy activity and an artificial skin sheet formed from the M cells. [Solution] GP2 contained in the M cells is transferred to the intracellular tight junction and galectin 9 is expressed in the M cells. Moreover, a structure is formed in which both GP2 and galectin 9 are present at the M cell surface.
申请公布号 US9265863(B2) 申请公布日期 2016.02.23
申请号 US201314438515 申请日期 2013.04.04
申请人 发明人 Fukunaga Hajime;Kopecko Dennis
分类号 C12N5/071;A61L27/60;A61L27/38;A61L27/54;A61F2/10 主分类号 C12N5/071
代理机构 Global IP Counselors, LLP 代理人 Global IP Counselors, LLP
主权项 1. An artificial skin sheet comprising: microfold cells (M cells) in which the glycoprotein 2 (GP2) contained in the M cells is located in tight junctions between the cells after having moved to the tight junctions, and in which galectin-9 is expressed.
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