发明名称 |
Orally available viridiofungin derivative possessing anti-HCV activity |
摘要 |
An object of the present invention is to provide a compound that is useful as an orally available anti-HCV agent. The present invention relates to a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. This compound has an anti-HCV activity and is useful as a medicine. |
申请公布号 |
US9266853(B2) |
申请公布日期 |
2016.02.23 |
申请号 |
US201314421577 |
申请日期 |
2013.08.16 |
申请人 |
Chugai Seiyaku Kabushiki Kaisha |
发明人 |
Kohchi Yasunori;Nakama Kimitaka;Komiyama Susumu;Watanabe Fumio |
分类号 |
C07D293/00;C07D317/00;C07D317/36;C07D293/06;C07D317/34;C07D317/40;C07C235/28;A61K31/192;A61K31/357;C07C235/74 |
主分类号 |
C07D293/00 |
代理机构 |
Foley & Larder LLP |
代理人 |
Foley & Larder LLP |
主权项 |
1. A compound represented by formula (1) below or a pharmaceutically acceptable salt thereof:wherein R is selected from a hydrogen atom and a group represented by formula (2) below:wherein
R1 is C1-10 alkyl; R2 is selected from a hydrogen atom, C1-6 alkyl, and aryl; R3 is selected from a hydrogen atom and C1-6 alkyl; R4 is C1-6 alkyl; and two Xs are the same or different, and each represent a halogen atom. |
地址 |
Tokyo JP |