发明名称 Orally available viridiofungin derivative possessing anti-HCV activity
摘要 An object of the present invention is to provide a compound that is useful as an orally available anti-HCV agent. The present invention relates to a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. This compound has an anti-HCV activity and is useful as a medicine.
申请公布号 US9266853(B2) 申请公布日期 2016.02.23
申请号 US201314421577 申请日期 2013.08.16
申请人 Chugai Seiyaku Kabushiki Kaisha 发明人 Kohchi Yasunori;Nakama Kimitaka;Komiyama Susumu;Watanabe Fumio
分类号 C07D293/00;C07D317/00;C07D317/36;C07D293/06;C07D317/34;C07D317/40;C07C235/28;A61K31/192;A61K31/357;C07C235/74 主分类号 C07D293/00
代理机构 Foley & Larder LLP 代理人 Foley & Larder LLP
主权项 1. A compound represented by formula (1) below or a pharmaceutically acceptable salt thereof:wherein R is selected from a hydrogen atom and a group represented by formula (2) below:wherein R1 is C1-10 alkyl; R2 is selected from a hydrogen atom, C1-6 alkyl, and aryl; R3 is selected from a hydrogen atom and C1-6 alkyl; R4 is C1-6 alkyl; and two Xs are the same or different, and each represent a halogen atom.
地址 Tokyo JP