发明名称 |
PÅVISNING AF ANTIGENFØLSOMME CELLER I EN PRØVE |
摘要 |
The present invention relates to methods for detecting antigen responsive cells in a sample using multidimensional labeled antigen presenting compounds, such as antigen-major histocompatibility complexes (NHC). Further, the present invention relates to the use of the present multidimensional labeled antigen presenting compounds, such as antigen-major histocompatibility complexes (MHC), for detecting antigen responsive cells in a sample, preferably a single sample, such as a blood sample. The present method allows high-throughput analysis of specific antigen responsive cells, such as T- and B-cells, thereby providing, for example, high-throughput methods for monitoring of diseases or conditions and the development of immunotherapeutics, vaccines, or the identification epitopes or immunogenic amino acid sequences. |
申请公布号 |
DK2362882(T3) |
申请公布日期 |
2016.02.22 |
申请号 |
DK20080875010T |
申请日期 |
2008.11.03 |
申请人 |
STICHTING SANQUIN BLOEDVOORZIENING;STICHTING HET NEDERLANDS KANKER INSTITUUT |
发明人 |
HADRUP, SINE, REKER;BAKKER, ARNOLD, HENDRIK;SHU, CHENG YI, JENNY;SCHUMACHER, ANTONIUS, NICOLAAS, MARIA |
分类号 |
C07K14/705;G01N33/569 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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