| 发明名称 |
Parasitic Biological Agents for Treatment and Prevention of Graft Versus Host Disease |
| 摘要 |
The invention relates to helminthic parasite preparations and their use for treatment or prevention of GVHD in a subject that has undergone a transplant. The invention also related to helminthic parasite preparations and their use for prevention of GVHD in a subject prior to a transplant. |
| 申请公布号 |
US2016045581(A1) |
申请公布日期 |
2016.02.18 |
| 申请号 |
US201514683778 |
申请日期 |
2015.04.10 |
| 申请人 |
University of Iowa Research Foundation |
发明人 |
Ince Mirac Nedim;Elliott David E.;Weiner George J. |
| 分类号 |
A61K39/00;G01N33/68;A61K9/00 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of decreasing the production of IFNγ and/or TNFα by donor regulatory T cells from a subject that has received a transplant, comprising administering a helminthic parasite preparation to the subject in an amount and for a time effective to decrease said production. |
| 地址 |
Iowa City IA US |
