主权项 |
1. A method of preparing two or more customized release dosage forms, comprising:
a. compressing two or more single cores, wherein said two or more single cores are to be used to prepare at least a first dosage form and a second dosage form, wherein each of said two or more single cores is the only core in the first dosage form and the second dosage form, respectively, wherein each of said two or more single cores is non-striated, wherein each of said two or more single cores has a length and a width, wherein each of said two or more single core's length is greater than its width, and wherein each of said two or more single cores comprises at least one active ingredient; and b. employing a dipping process to partially coat at least one surface portion of each of the two or more single cores with a modified release coating, wherein the length of the coating on the long (i.e., latitudinal) axis of a first of said two or more single cores differs from the length of the coating on the long axis of a second of said two or more single cores in accordance with a desired release rate of the active ingredient from the first dosage form and the second dosage form, respectively, wherein a desired release rate of said first dosage form differs from a desired release rate of said second dosage form; and wherein the customized release dosage forms do not comprise shells. |