发明名称 PC-O 44:4—a biomarker for visceral adiposity
摘要 The present invention generally relates to the field of biomarkers. In particular, the present invention relates to biomarkers such as PC-O 44:4 that can be used, for example for detecting and/or quantifying visceral adiposity and/or changes in visceral adiposity. This biomarker may also be used to diagnosing the effect of a change in lifestyle on visceral adiposity in a subject.
申请公布号 US9261520(B2) 申请公布日期 2016.02.16
申请号 US201414553133 申请日期 2014.11.25
申请人 NESTEC S.A. 发明人 Martin Francois-Pierre;Montoliu Roura Ivan;Guy Philippe Alexandre;Rezzi Serge Andre Dominique
分类号 G01N33/92;G01N33/48;C07F9/09 主分类号 G01N33/92
代理机构 Kilpatrick Townsend & Stockton LLP 代理人 Kilpatrick Townsend & Stockton LLP
主权项 1. A method of diagnosing the effect of a change in lifestyle on visceral adiposity in a subject, comprising: determining a level of PC-O 44:4 in a body fluid sample previously obtained from a subject to be tested after the change in lifestyle, and comparing the subject's PC-O 44:4 level to a predetermined reference value, wherein the predetermined reference value is based on a PC-O 44:4 level in the same body fluid obtained from the same subject prior to the lifestyle change, and wherein an increased PC-O 44:4 level in the sample compared to the predetermined reference value indicates a positive effect of the change in lifestyle on visceral adiposity.
地址 Vevey CH