SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES XIA
摘要
The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are as defined in the description). The compounds of the general formula (I) are inhibitors of factor XIa, and are useful in the prevention of and/or therapy for thromboembolic diseases.
申请公布号
HK1207854(A1)
申请公布日期
2016.02.12
申请号
HK20150104626
申请日期
2015.05.15
申请人
ONO PHARMACEUTICAL CO. LTD.
发明人
IMAGAWA, AKIRA;KONDO, TAKASHI;NISHIYAMA, TAIHEI;COURTNEY, STEVE;YARNOLD, CHRIS;ICHIHARA, OSAMU;FLANAGAN, STUART