Molecules to perfect HbA1c levels

摘要

This invention is of particular use to patients with Diabetes Mellitus. It uses alkyl analogs of the methyl pyruvate (MP) family to provide energy and improve insulin and glucose homeostasis via accelerated intracellular delivery of protons and ATP from each MP. The energy upregulates cellular cross talk and networking resulting in a surge of ATP enabling NADH (via glycolysis) that enables pancreatic islet cells to obtain increased ATP allowing excess insulin manufacture. This process improves cellular respiration and expedites protein, lipid and hormone manufacture. The increased energy also enables telomeres and delays Hayflick limit. Instead of cellular repair, silence, or apoptosis, energy is allocated for cell/organ function. This invention curbs inflammation and ROS by idealizing cellular respiration and diminishing hyperglycemia. In turn a reduction of advanced glycation end products (AGEs), lessened target RNA and nucleic acid toxins, i.e., diminished HbA1c occurs. By decreased drain of cellular energy, genomic function improves.

主权项

1. A method of treating a patient afflicted with Diabetes Mellitus to reduce HbA1c of said patient in which energy is provided to energy deprived cells of said patient, said method consisting of administering, to said patient afflicted with said Diabetes Mellitus, a therapeutically effective amount of methyl pyruvate and ethyl pyruvate together with at least one additional agent, so as to provide said energy to said energy deprived cells via a citric acid cycle and so as to reduce said HbA1c of said patient;
wherein said at least one additional agent is selected from the group consisting of acetyl L-carnitine, taurine, inosine, magnesium chloride, magnesium L-threonate, alpha lipoic acid, vitamin E in the form of alpha and gamma tocopherol, vitamin D3 and niacin.