发明名称 |
Methods of administration of Substance P for wound healing |
摘要 |
The present invention relates to a use of Substance-P for the manufacture of a medicament for mobilization or proliferation of Mesenchymal stem cells (MSCs) from the bone marrow, or facilitating said mobilization or proliferation, and use of Substance-P for the manufacture of a medicament for wound-healing or facilitating wound-healing. |
申请公布号 |
US9254305(B2) |
申请公布日期 |
2016.02.09 |
申请号 |
US201314018772 |
申请日期 |
2013.09.05 |
申请人 |
Korea Institute of Radiological & Medical Sciences;Chung-Ang University Industry-Academy Cooperation Foundation |
发明人 |
Son Young Sook;Hong Hyun Sook;Kim Jae Chan |
分类号 |
A01N63/00;A61K38/04;A61K35/28 |
主分类号 |
A01N63/00 |
代理机构 |
Locke Lord LLP |
代理人 |
Zerhusen Bryan D.;Locke Lord LLP |
主权项 |
1. A method of healing or facilitating healing of an epithelial wound in a mammal, comprising:
a) administering Substance-P intravenously to a mammal having an epithelial wound, b) isolating mesenchymal stem cells (MSCs) from the bone marrow of the mammal of a), and c) administering the MSCs to the mammal intravenously such that the epithelial wound is healed. |
地址 |
Seoul KR |