A METHOD FOR THE IDENTIFICATION OF IMMUNOTHERAPY-DRUG COMBINATIONS USING A NETWORK APPROACH

摘要

This invention relates to systems and methods for evaluating the differentiality of a set of discrete random variables between two or more conditions, such as a malignant condition responding to treatment regime and one that is not. It also provides for the identification and selection of drugs that act in coordinated manner to phenocopy a genetic network of a malignant condition that responds to at least an immune checkpoint blockade agent.