SPECIFIC OLIGOPEPTIDES AS ANTI-ANGIOGENIC DRUGS

摘要

The subject matter of the invention is an oligopeptide isolated from an SCO‐spondin glycoprotein, characterised by the following sequence: ‐W‐S‐X1‐W‐S‐ X2‐C‐S‐ X3‐X4‐C‐G‐ (SEQ ID N°1), wherein X1, X2, X3 and X4 represent sequences of 1 to 5 amino acids, for the use thereof as a drug for inhibiting angiogenesis, in the treatment of diseases associated with angiogenesis in humans or animals, in particular as a drug against tumour angiogenesis. The oligopeptide is suitable in particular for the treatment of brain tumours.