发明名称 SUBSTITUTED 5-(3,5-DIMETHYLISOXAZOL-4-YL)INDOLINE-2-ONES
摘要 Disclosed are substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compounds, pharmaceutical compositions comprising at least one such 4 substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compound processes for the preparation thereof, and the use thereof for inhibiting BET family of bromodomains and for treating disorders mediated thereby, such as certain cancers.
申请公布号 US2016030395(A1) 申请公布日期 2016.02.04
申请号 US201414404798 申请日期 2014.04.14
申请人 BeiGene, Ltd. 发明人 REN Bo;ZHOU Changyou;WANG Hexiang
分类号 A61K31/422;A61K31/5377;A61K31/454;A61K31/496;C07D413/04;C07D413/14 主分类号 A61K31/422
代理机构 代理人
主权项
地址 Camana Bay, Grand Cayman, Cayman Islands GB