发明名称 |
SUBSTITUTED 5-(3,5-DIMETHYLISOXAZOL-4-YL)INDOLINE-2-ONES |
摘要 |
Disclosed are substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compounds, pharmaceutical compositions comprising at least one such 4 substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compound processes for the preparation thereof, and the use thereof for inhibiting BET family of bromodomains and for treating disorders mediated thereby, such as certain cancers. |
申请公布号 |
US2016030395(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
US201414404798 |
申请日期 |
2014.04.14 |
申请人 |
BeiGene, Ltd. |
发明人 |
REN Bo;ZHOU Changyou;WANG Hexiang |
分类号 |
A61K31/422;A61K31/5377;A61K31/454;A61K31/496;C07D413/04;C07D413/14 |
主分类号 |
A61K31/422 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Camana Bay, Grand Cayman, Cayman Islands GB |