发明名称 |
ANTIBODIES WITH HIGH AFFINITY FOR AKLOTHO |
摘要 |
An antibody and/or binding fragment thereof, wherein the antibody and/or binding fragment thereof specifically binds to an epitope of a aKlotho polypeptide, optionally a folded aKiotho or optionally with a dissociation constant (KD) of about 2 nM or less, as measured by competitive ELISA assay, methods 0 of making and using to diagnose kidney diseases. |
申请公布号 |
CA2955039(A1) |
申请公布日期 |
2016.02.04 |
申请号 |
CA20152955039 |
申请日期 |
2015.07.31 |
申请人 |
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
BARKER, SARAH L.;MOE, ORSON W.;KURO-O, MAKOTO;SIDHU, SACHDEV S. |
分类号 |
C12N15/13;C07K16/28;G01N33/543 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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