ULTRASOUND WAVEFORM TOMOGRAPHY METHOD AND SYSTEM

摘要

A method and system for generating an enhanced image of a volume of tissue, the method comprising: emitting acoustic waveforms toward the volume of tissue; detecting a set of acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating, from the set of acoustic signals, an initial model representing a distribution of an acoustomechanical parameter across a region of the volume of tissue; extracting a set of frequency components, from the set of acoustic signals; generating a first simulated wavefield with a first frequency component of the set of frequency components; generating an updated model of the initial model with the first simulated wavefield; iteratively refining the updated model with a set of simulated wavefields associated with the set of frequency components until a threshold condition is satisfied, thereby producing a final model; and generating the enhanced image from the final model of the volume of tissue.

主权项

1. A method for generating an enhanced image of a volume of tissue, the method comprising:
With a transducer comprising an array of ultrasound transmitters and an array of ultrasound receivers and configured to surround the volume of tissue, emitting acoustic waveforms toward the volume of tissue with the array of ultrasound transmitters; detecting, with the array of ultrasound receivers, a set of acoustic signals derived from acoustic waveforms transmitted through the volume of tissue; at a computing system in communication with the transducer, generating, from the set of acoustic signals, an initial sound speed model representing a distribution of sound speed across a region of the volume of tissue; at the computing system, extracting a subset of a frequency spectrum, including a set of frequency components, from the set of acoustic signals; at the computing system, generating a first simulated wavefield with a first frequency component of the set of frequency components, according to a forward modeling process; at the computing system, generating an updated model of the initial sound speed model based upon a solution to an inverse problem generated with the first simulated wavefield; iteratively refining the updated model with solutions to the inverse problem generated with a set of simulated wavefields associated with the set of frequency components until a threshold condition is satisfied, thereby producing a final sound speed model; and at a display in communication with the computing system, rendering a sound speed image, generated from the final sound speed model of the volume of tissue.