| 发明名称 | Antibodies against human CD38 | ||
| 摘要 | Isolated monoclonal antibodies which bind to human CD38 and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies. | ||
| 申请公布号 | US9249226(B2) | 申请公布日期 | 2016.02.02 |
| 申请号 | US201113702857 | 申请日期 | 2011.06.08 |
| 申请人 | GENMAB A/S | 发明人 | de Weers Michel;Walseth Tim;van de Winkel Jan;Vink Tom;Parren Paul |
| 分类号 | C07K16/30;C07K16/28;A61K39/395;A61K45/06 | 主分类号 | C07K16/30 |
| 代理机构 | Nelson Mullins Riley & Scarborough LLP | 代理人 | Nelson Mullins Riley & Scarborough LLP ;Remillard, Esq. Jane E.;Frank Christopher L. |
| 主权项 | 1. An isolated antibody that binds to human CD38, which antibody is encoded by a human heavy chain nucleic acid comprising a nucleotide sequence in its variable region as set forth in SEQ ID NO: 1, 6, 11, 16 or 21, and a human light chain nucleic acid comprising a nucleotide sequence in its variable region as set forth in SEQ ID NOs: 26, 31, 36, 41 or 46. | ||
| 地址 | Copenhagen DK | ||