发明名称 |
BISPECIFIC HER2 AND CD3 BINDING MOLECULES |
摘要 |
<p>Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to CD3, a T cell receptor, and mediate T cell cytotoxicity for managing and treating disorders, such as cancer. Also provided herein are uses and methods for managing and treating HER2 -related cancers.</p> |
申请公布号 |
WO2016014942(A1) |
申请公布日期 |
2016.01.28 |
申请号 |
WO2015US41989 |
申请日期 |
2015.07.24 |
申请人 |
MEMORIAL SLOAN KETTERING CANCER CENTER |
发明人 |
CHEUNG, NAI-KONG V.;LOPEZ-ALBAITERO, ANDRES;XU, HONG |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C07K16/32;C07K16/46 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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