发明名称 |
CELLULAR DELIVERY OF DNA INTERCALATING AGENTS |
摘要 |
Compositions and methods for targeted delivery of active agents to cells are provided. The compositions comprise a wholly or partially double-stranded synthetic DNA carrier, and an active agent intercalated in double-stranded portions of the DNA carrier. The DNA carrier may also be linked to a targeting agent. The compositions are useful for delivering an active agent into a targeted cell type, for example a cytotoxic agent. |
申请公布号 |
EP2976109(A1) |
申请公布日期 |
2016.01.27 |
申请号 |
EP20140725290 |
申请日期 |
2014.03.19 |
申请人 |
GENISPHERE, LLC |
发明人 |
GETTS, ROBERT, C.;KADUSHIN, JAMES;GEORGE-WEINSTEIN, MINDY;GERHART, JACQUELYN;DYLGJERI, EMANUELA;RHODES, KELLY |
分类号 |
A61K47/48;A61K31/704;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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