发明名称 |
Systems, devices, and methods for agglutination assays using sedimentation |
摘要 |
Embodiments of the present invention include methods for conducting agglutination assays using sedimentation. Aggregates may be exposed to sedimentation forces and travel through a density medium to a detection area. Microfluidic devices, such as microfluidic disks, are described for conducting the agglutination assays, as are systems for conducting the assays. |
申请公布号 |
US9244065(B1) |
申请公布日期 |
2016.01.26 |
申请号 |
US201213423073 |
申请日期 |
2012.03.16 |
申请人 |
Sandia Corporation |
发明人 |
Schaff Ulrich Y.;Sommer Gregory J.;Singh Anup K. |
分类号 |
G01N33/543;G01N33/537;B01D21/26;B01L3/00;G01N33/538 |
主分类号 |
G01N33/543 |
代理机构 |
Dorsey & Whitney LLP |
代理人 |
Dorsey & Whitney LLP |
主权项 |
1. A method comprising:
layering a mixture on a density medium, wherein the mixture includes a sample and a first population of coated beads having a first density, wherein the first population of coated beads include affinity reagents for an analyte of interest, wherein the first population of coated beads is configured to form aggregates with the analyte interest when present, wherein the density medium has a minimum density greater than the first density; subjecting the mixture to sedimentation forces such that the aggregates, if formed, travel through the density medium; and detecting a presence of the aggregates in a detection area. |
地址 |
Albuquerque NM US |