| 主权项 |
1. A compound, or a pharmaceutically acceptable salt, ester or prodrug thereof having Formula II-i wherein R1 is optionally substituted alkyl, optionally substituted alkenyl, alkynyl haloalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted carbocycle, optionally substituted heterocycle, halo, H, optionally substituted alkoxy, optionally substituted amine, cyano, or optionally substituted arylalkyl; R2 is selected from an optionally substituted C1-C8 alkyl, haloalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted carbocycle, optionally substituted heterocycle, halo, H, —OH, optionally substituted alkoxy, optionally substituted amino, cyano, or optionally substituted arylalkyl; R4 is halo, OR5, NR5R6, NR5C(═O)R6, or R5 and R6 are independently null, H, —OH, ═O, halo, haloalkyl, alkyl, alkynyl, alkenyl, aryl, arylalkyl, heteroaryl, carbocyle, heterocycle, cyano, alkoxy, amino or, wherein R5 and R6 can be further substituted; and R10 is C, N, O, or S. |
