发明名称 |
4-CYANO-N-(2-(4,4-DIMETHYLCYCLOHEX-1-EN-1-YL)-6-(2,2,6,6-TETRAMETHYLTETRAHYDRO-2H-PYRAN-4-YL)PYRIDIN-3-YL)-1H-IMIDAZOLE-2-CARBOXAMIDE FOR THE TREATMENT OF HODGKIN'S LYMPHOMA |
摘要 |
The present invention is directed to methods for the treatment of Hodgkin's lymphoma comprising administering to a patient in need thereof, a therapeutically effective amount of 4-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6 -(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)-1H-imidazole-2-carboxamide as mono-therapy or as combination or co-therapy with one or more chemotherapeutic agent or chemotherapy regimens. |
申请公布号 |
US2016015700(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
US201414772027 |
申请日期 |
2014.03.13 |
申请人 |
DE BOER Carla;ELSAYED Yusri A.;KHAN Imran;MANTHEY Carl L.;SYNDER Linda;JANSSEN PHARMACEUTICA NV |
发明人 |
DE BOER Carla;ELSAYED Yusri A.;KHAN Imran;MANTHEY Carl L.;SNYDER Linda |
分类号 |
A61K31/4439;A61K31/573;A61K31/7048;A61K31/704;A61K31/655;A61K31/475;A61K38/14;A61K45/06;A61K31/675 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
1. A method for the treatment of Hodgkin's Lymphoma comprising administering to a patient in need thereof, a therapeutically effective amount of a compound of formula (I)or a tautomer or pharmaceutically acceptable salt thereof. |
地址 |
Leiden NL |