| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to field of chemistry and can be applied in medicine as marker in research of liver and myocardium metabolism. Method for obtaining linoleic acid includes obtaining 7-chloroheptanoic acid methyl ether or 7-iodineheptanoic acid methyl ether, condensation of 1-chloroundecaine-2,5 with 7-chlorheptanoic acid methyl ether or with 7-iodineheptanoic acid methyl ether, and hydration of obtained methyl ether of octadiin-9,12-oic-1 acid with further saponification of obtained octadiin-9,12-oic-1 acid methyl ether to octadecadien-9,12-oic-1 acid (linoleic acid), with stages of reaction of obtaining methyl ethers, reaction of condensation in presence of magnesium and reaction of hydration in presence of palladium catalyst being carried out in field of ultrasonic radiation with power 300 W and frequency 22 kHz.EFFECT: reduction of process time and increase of target product output.1 tbl |
