发明名称 Method for screening compounds for alpha1B adrenergic receptor antagonist and analgesic activity
摘要 A method for identifying compounds that can be useful for producing analgesia is disclosed. In particular, the method involves providing preparation of a cell, that expresses an alpha1B adrenergic receptor, combining a test compound with the cell preparation, measuring the effect of the test compound on the alpha1B receptor activity, and evaluating the compound thus identified for analgesic activity.
申请公布号 US6733982(B1) 申请公布日期 2004.05.11
申请号 US20000520584 申请日期 2000.03.08
申请人 SYNTEX (U.S.A.) LLC 发明人 FORD ANTHONY P. D. W.;WILLIAMS TIMOTHY JAMES;GOGAS KATHLEEN RUTH;JACOBSON LUPITA O.
分类号 A61K31/00;A61K45/06;C07D263/42;C07D263/58;C07D413/04;C07D413/06;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;C07D487/04;G01N33/94;(IPC1-7):C07K1/00;C07H21/04;C12N1/20;C12P21/06;G01N33/566 主分类号 A61K31/00
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