| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a compound of general formulaand its pharmaceutically acceptable salts and stereoisomers possessing anti-cancer activity, a based pharmaceutical composition, using them and a method of treating cancer with using them. In general formula I Rand Rare specified in hydrogen and halogen; R, R, R, R, R, R, Rand Rmean hydrogen; Rmeans -OH; R, Rand Rmean unsubstituted C-Calkyl; Ris specified in hydrogen, =O and OR, wherein Rmeans unsubstituted C-Calkyl; Ris specified in unsubstituted C-Calkyl, OH-substituted C-Calkyl and COH; Rmeans -OH; and the line ----- represents either a bond, or an epoxy group.EFFECT: producing pharmaceutically acceptable salts and stereoisomers possessing anti-cancer activity.17 cl, 10 tbl, 5 ex |
