发明名称 |
TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS. |
摘要 |
Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease. |
申请公布号 |
MX2015011766(A) |
申请公布日期 |
2016.01.15 |
申请号 |
MX20150011766 |
申请日期 |
2014.03.14 |
申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
MCMINN, DUSTIN;JOHNSON, HENRY;BOWERS, SIMEON;MOEBIUS, DAVID, C. |
分类号 |
C07D405/12;A61K31/336;A61K31/404;C07D303/32;C07D409/12 |
主分类号 |
C07D405/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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