METHOD FOR OBTAINING ANTIBODIES

摘要

PROBLEM TO BE SOLVED: To provide a method for manufacturing recombinant antibody molecules.SOLUTION: The present disclosure relates to a method for manufacturing recombinant antibody molecules comprising culturing a host cell sample transformed with an expression vector encoding a recombinant antibody molecule; adding an extraction buffer to the sample; and subjecting the sample to a heat treatment step; wherein the pH of the sample is detected after addition of the extraction buffer, and optionally adjusted, to ensure that the pH of the sample is 6 to 9 prior to the heat treatment step.